| Rank | Website | Founders | Annual Revenue | Per Second |
| 1 | Google | Larry Page and Sergey Brin | $21,800,000,000 | $691.27 |
| 2 | Amazon | Jeff Bezos | $19,166,000,000 | $607.75 |
| 3 | Yahoo | Jerry Yang and David Filo | $7,200,000,000 | $228.31 |
| 4 | eBay | Pierre Omidyar | $6,290,000,000 | $199.45 |
| 5 | MSN/Live | Nathan Myhrvold. | $3,214,000,000 | $101.92 |
| 6 | PayPal | Max Levchin, Peter Thiel, and Luke Nosek | $2,250,000,000 | $71.35 |
| 7 | iTunes | Jeff Robbin | $1,900,000,000 | $60.25 |
| 8 | Reuters | Marshal Vace | $1,892,000,000 | $59.99 |
| 9 | Priceline | Jesse Fink | $1,884,000,000 | $59.74 |
| 10 | Expedia | Added Mark Schroeder | $1,447,000,000 | $45.88 |
| 11 | NetFlix | Reed Hastings | $1,200,000,000 | $38.05 |
| 12 | Travelocity | Terry Jones | $1,100,000,000 | $38.05 |
| 13 | Zappos | Nick Swinmurn | $1,000,000,000 | $31.71 |
| 14 | Hotels.com | David Litman | $1,000,000,000 | $31.71 |
| 15 | AOL | Erik Prince | $968,000,000 | $30.70 |
| 16 | Orbitz | Jeff Katz | $870,000,000 | $27.59 |
| 17 | Overstock | Robert Brazell | $834,000,000 | $26.45 |
| 18 | MySpace | Tom Anderson | $800,000,000 | $25.37 |
| 19 | Skype | Niklas Zennstrom | $550,841,000 | $17.47 |
| 20 | Sohu | Zhang Chaoyang | $429,000,000 | $13.60 |
| 21 | Buy.com | Robb Brock | $400,000,000 | $12.68 |
| 22 | StubHub | Eric Baker | $400,000,000 | $12.68 |
| 23 | Alibaba | Jack Ma | $316,000,000 | $10.02 |
| 24 | Facebook | Mark Zuckerberg | $300,000,000 | $9.51 |
| 25 | YouTube | Chad Hurley, Steve Chen and Jawed Karim | $300,000,000 | $9.51 |
| 26 | Blue Nile | Mark Vadon | $295,000,000 | $9.35 |
| 27 | Tripadvisor | Stephen Kaufer | $260,000,000 | $8.24 |
| 28 | Getty Images | Mark Getty | $233,200,000 | $7.39 |
| 29 | Bidz | Garry Itkin | $207,000,000 | $6.56 |
| 30 | NYTimes | Henry Jarvis Raymond | $175,000,000 | $5.55 |